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Tetanus in Dogs

By Otto M. Radostits, CM, DVM, MSc, DACVIM (Deceased), Professor Emeritus, Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan ; David A. Ashford, DVM, MPH, DSc, Assistant Area Director, International Services, APHIS, USDA ; Craig E. Greene, DVM, MS, Professor, Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia ; Eugene D. Janzen, DVM, MVS, Professor, Production Animal Health, Faculty of Veterinary Medicine, University of Calgary ; Bert E. Stromberg, PhD, Professor, Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota ; Max J. Appel, DMV, PhD, Professor Emeritus ; Stephen C. Barr, BVSc, MVS, PhD, DACVIM, Professor of Medicine, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University ; J. P. Dubey, MVSc, PhD, Microbiologist, Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research Center, USDA ; Paul Ettestad, DVM, MS, State Public Health Veterinarian, Epidemiology and Response Division, New Mexico Department of Health ; Kenneth R. Harkin, DVM, DACVIM, Associate Professor, College of Veterinary Medicine, Kansas State University ; Delores E. Hill, PhD, Parasitologist, U.S. Department of Agriculture ; Johnny D. Hoskins, DVM, PhD, Small Animal Consultant ; Jodie Low Choy, BVSc, BVMS, IVAS Cert, Menzies School of Health Research; University Avenue Veterinary Hospital, Northern Territory, Australia ; Barton W. Rohrbach, VMD, MPH, DACVPM, Associate Professor, Department of Comparative Medicine, Veterinary Teaching Hospital, University of Tennessee ; J. Glenn Songer, PhD, Professor, Department of Veterinary Science and Microbiology, University of Arizona ; Joseph Taboada, DVM, DACVIM, Professor and Associate Dean, Office of Student and Academic Affairs, School of Veterinary Medicine, Louisiana State University ; Charles O. Thoen, DVM, PhD, Professor, Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University ; John F. Timoney, MVB, PhD, Dsc, MRCVS, Keeneland Chair of Infectious Diseases, Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky ; Ian Tizard, BVMS, PhD, DACVM, University Distinguished Professor of Immunology; Director, Richard M. Schubot Exotic Bird Health Center, Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University

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Tetanus toxemia is caused by a specific poison, or toxin, that blocks inhibitory nerve signals, leading to severe muscle contractions and exaggerated muscle responses to stimuli. The toxin is produced by Clostridium tetani bacteria in dead tissue. Almost all mammals are susceptible to this disease, although dogs are relatively resistant.

Clostridium tetani is found in soil and intestinal tracts. In most cases, it is introduced into the body through wounds, particularly deep puncture wounds. Sometimes, the point of entry cannot be found because the wound itself may be minor or healed. The bacteria remain in the dead tissue at the original site of infection and multiply. As bacterial cells die and disintegrate, the potent nerve toxin is released. The toxin causes convulsions of the voluntary muscles.

Dogs with tetanus usually stand with stiff legs.

The incubation period varies from 1 to several weeks but usually averages 10 to 14 days. Localized stiffness, often involving the jaw muscles and muscles of the neck, the hind limbs, and the region of the infected wound, is seen first. General stiffness becomes pronounced about 1 day later, and then spasms and painful sensitivity to touch become evident. Spasms are often triggered by sudden movement or noise. Because of their high resistance to tetanus toxin, dogs often have a long incubation period and frequently develop tetanus that is localized to the area of the wound. However, generalized tetanus does develop, in which the ears are erect, the tail is stiff and extended, and the mouth is partially open with the lips drawn back.

In the early stages of the disease, your veterinarian may recommend muscle relaxants, tranquilizers, or sedatives along with tetanus antitoxin. This treatment is supported by draining and cleaning the wounds and administering antibiotics.

Good nursing is invaluable during the early period of spasms. If your pet has tetanus and will be returning home with you rather than staying in a clinic, be sure to follow the nursing care instructions fully and carefully.

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