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Find information on animal health topics, written for the veterinary professional.

* This is the Veterinary Version. *

Plague in Dogs

By Otto M. Radostits, CM, DVM, MSc, DACVIM (Deceased), Professor Emeritus, Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan ; David A. Ashford, DVM, MPH, DSc, Assistant Area Director, International Services, APHIS, USDA ; Craig E. Greene, DVM, MS, Professor, Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia ; Eugene D. Janzen, DVM, MVS, Professor, Production Animal Health, Faculty of Veterinary Medicine, University of Calgary ; Bert E. Stromberg, PhD, Professor, Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota ; Max J. Appel, DMV, PhD, Professor Emeritus ; Stephen C. Barr, BVSc, MVS, PhD, DACVIM, Professor of Medicine, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University ; J. P. Dubey, MVSc, PhD, Microbiologist, Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research Center, USDA ; Paul Ettestad, DVM, MS, State Public Health Veterinarian, Epidemiology and Response Division, New Mexico Department of Health ; Kenneth R. Harkin, DVM, DACVIM, Associate Professor, College of Veterinary Medicine, Kansas State University ; Delores E. Hill, PhD, Parasitologist, U.S. Department of Agriculture ; Johnny D. Hoskins, DVM, PhD, Small Animal Consultant ; Jodie Low Choy, BVSc, BVMS, IVAS Cert, Menzies School of Health Research; University Avenue Veterinary Hospital, Northern Territory, Australia ; Barton W. Rohrbach, VMD, MPH, DACVPM, Associate Professor, Department of Comparative Medicine, Veterinary Teaching Hospital, University of Tennessee ; J. Glenn Songer, PhD, Professor, Department of Veterinary Science and Microbiology, University of Arizona ; Joseph Taboada, DVM, DACVIM, Professor and Associate Dean, Office of Student and Academic Affairs, School of Veterinary Medicine, Louisiana State University ; Charles O. Thoen, DVM, PhD, Professor, Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University ; John F. Timoney, MVB, PhD, Dsc, MRCVS, Keeneland Chair of Infectious Diseases, Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky ; Ian Tizard, BVMS, PhD, DACVM, University Distinguished Professor of Immunology; Director, Richard M. Schubot Exotic Bird Health Center, Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University

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Plague is a sudden and sometimes fatal bacterial disease caused by Yersinia pestis. It is transmitted primarily by the fleas of rats and other rodents. This is the disease, often called the Black Death, that swept through Asia and then Europe in the 14th century. Over 25 million people (one third of the population) died of this disease in Europe between 1347 and 1352. Devastating outbreaks of this disease recurred with regularity throughout the next 200 years.

Today, this disease can be controlled with antibiotics and other medications; however, it has not been eradicated. Small numbers of cases occur in wild animals in the western United States and throughout the world, including Eurasia, Africa, and North and South America. On average, 10 human plague cases are reported each year in the United States; the majority are from New Mexico, California, Colorado, and Arizona. Infection in dogs is extremely rare.

Yersinia pestis is maintained in the environment in a natural cycle between susceptible rodent species and their associated fleas. Commonly affected rodent species include ground squirrels and wood rats. Dogs are usually exposed to the bacteria by oral contact with secretions or tissues of an infected rodent or rabbit or by the bite of an infected flea. Potentially, the infected fleas can be transported into homes.

Dogs are inherently resistant to the plague-causing bacteria. Dogs that do become infected with plague are less likely to show signs illness than cats. Signs of infection include fever, lethargy, inflammation of the lymph nodes below the lower jaw, a pus-like lesion along the jaw, lesions in the mouth, and cough.

Due to the rapid progression of this disease, treatment for suspected plague (and infection control practices) should be started before a definitive diagnosis is obtained. Your veterinarian will recommend an antibiotic as standard treatment.

Along with treatment and diagnostic considerations, protection of people and other animals and initiation of public health interventions are critical when an animal is suspected to have plague. Even before a diagnosis is complete, animals with signs suggestive of plague should be placed in isolation and infection control measures implemented to protect you and your family, other household pets, and any other animals or individuals that have had contact with the infected pet.

To decrease the risk of pets and humans being exposed to plague, pet owners in areas where the disease may be found should keep their pets from roaming and hunting, limit their contact with rodent or rabbit carcasses, and use appropriate flea control. Your veterinarian can suggest the most appropriate flea control product for your pet.

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* This is the Veterinary Version. *