Not Found
Locations

Find information on animal health topics, written for the veterinary professional.

* This is the Veterinary Version. *

Topical Preparations (Toxicity)

By Safdar A. Khan, DVM, MS, PhD, DABVT, Director of Toxicology Research, ASPCA Animal Poison Control Center, Urbana, Illinois

Zinc Oxide

Zinc oxide ointments or creams are commonly used as topical skin protectants, astringents, and bactericidal agents. Most ointments contain 10%–40% zinc oxide. Acute ingestion of zinc oxide–containing products usually results in gastric irritation (vomiting) and diarrhea, without the intravascular hemolysis and liver and renal damage associated with ingestion of elemental zinc. Signs are usually seen within 2–4 hr of a significant exposure. Vomiting animals should be managed symptomatically and supportively. Some dogs show hypersensitivity-type reactions manifested by facial and ocular edema. Such cases can be treated with diphenhydramine or other antiallergic medications.

* This is the Veterinary Version. *