Canine blood smear, regenerative anemia
Courtesy of Dr. John W. Harvey.
A regenerative anemia with increased polychromasia and acanthocytosis in blood from a dog with hemangiosarcoma. A neutrophil and a nucleated erythrocyte (metarubricyte) are also present (Wright-Giemsa, 100X oil immersion). Acanthocytes are commonly seen in this disorder when metastatic liver infiltrates occur.