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Autoimmune hemolytic anemia, blood smear (100X), dog

Courtesy of Dr. John W. Harvey.

Blood smear from a dog with autoimmune hemolytic anemia (Wright-Giemsa, 100X oil immersion). Erythrocytes exhibit increased polychromasia and anisocytosis, with many spherocytes present. Spherocytes lack central pallor and are of smaller diameter than other cells present.