|
Hypertrophic Osteodystrophy |  |
| Hypertrophic osteodystrophy is a developmental disorder of the metaphyses in long bones of young, growing dogs, usually of a large or giant breed. The exact etiology is unknown, although excessive dietary supplementation is suspected. The pathophysiology is based on metaphyseal vascular impairment leading to a failure in ossification and trabecular necrosis and inflammation. |
| Clinical signs include bilateral metaphyseal pain and swelling in the distal radius and ulna, fever, anorexia, and depression. Clinical signs may be periodic. Angular limb deformities may develop in severely affected dogs. Radiography reveals metaphyseal bone lucencies and circumferential periosteal bone formation. |
| Therapy is symptomatic and aimed at relieving pain (eg, NSAID), reducing dietary supplementation, and providing supportive fluid care. |
