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Tricuspid Dysplasia


Congenital malformation of the tricuspid valve complex is seen occasionally in dogs and cats. Breeds predisposed are Labrador Retrievers and German Shepherds. Tricuspid dysplasia results in tricuspid insufficiency and systolic regurgitation of blood into the right atrium. Rarely, tricuspid valve stenosis can be noted. Chordae tendineae are commonly shortened or absent, and tricuspid valve leaflets may be thickened or adhered to the ventricular or intraventricular septal wall. Other concurrent congenital anomalies such as mitral valve dysplasia, septal defects, subaortic stenosis, or pulmonic stenosis may be present. In Ebstein's anomaly, a variant of tricuspid dysplasia, the tricuspid valve is displaced toward the cardiac apex.

Fig. 6

Malformation of the tricuspid valve results in significant valvular insufficiency. Chronic tricuspid regurgitation leads to volume overload of the right heart, dilating the right ventricle and atrium. Pulmonary blood flow may be decreased, resulting in fatigue and tachypnea. As the pressure in the right atrium increases, venous return is impaired, causing ascites.

Clinical signs correlate with the severity of the defect. Affected animals usually display signs of right-sided CHF. A harsh holosystolic murmur of tricuspid regurgitation is prominent at the right cardiac apex. Atrial arrhythmias, especially paroxysmal atrial tachycardia, are common and may cause death. Electrocardiography and radiography typically demonstrate right ventricular and right atrial enlargement. The caudal vena cava may be significantly enlarged. Echocardiography demonstrates malformation of the tricuspid valve and usually severe right atrial and ventricular dilatation. Doppler echocardiography demonstrates severe tricuspid regurgitation.

Prognosis for animals with clinical signs is guarded. Periodic abdominocentesis may be needed to control peritoneal effusions. Diuretics, vasodilators, and digoxin may also be indicated.

Last full review/revision April 2012 by Davin Borde, DVM, DACVIM

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