THE MERCK VETERINARY MANUAL
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Subinvolution of Placental Sites (SIPS) in Small Animals

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Subinvolution of placental sites (SIPS) is abnormal repair of the endometrial placental sites. This disorder is most common in young bitches (<3 yr old) after whelping a first litter. Bitches with SIPS are normal except for hemorrhagic uterine discharge passing from the vulva for several weeks postpartum. Diagnosis is by exclusion; differentials include metritis, vaginitis, and cystitis. Treatment is supportive. Ovariohysterectomy is recommended for bitches that become anemic enough to require transfusion and for bitches not intended for future breeding.

Last full review/revision November 2013 by Mushtaq A. Memon, BVSc, PhD, DACT

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