Toxicities from Human Drugs

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• Toxicities from Over-the-Counter Drugs

• Cold and Cough Medications (Toxicity)
  • Antihistamines
    • Treatment:
  • Dextromethorphan

• Decongestants (Toxicity)
  • Imidazoline Decongestants
    • Clinical Findings:
    • Treatment:
  • Phenylephrine
  • Pseudoephedrine and Ephedrine
    • Clinical Findings:
    • Treatment:

• Analgesics (Toxicity)
  • Over-the-Counter Nonsteroidal Anti-inflammatory Drugs
    • Treatment:
  • Acetaminophen
    • Treatment:

• Gastrointestinal Drugs (Toxicity)
  • H2-Receptor Antagonists
  • Antacids

• Multivitamins and Iron (Toxicity)

• Topical Preparations (Toxicity)
  • Zinc Oxide

• Herbal Supplements (Toxicity)
  • Ma Huang (Ephedrine) and Guarana (Caffeine)
  • 5-Hydroxytryptophan

• Toxicities from Prescription Drugs

• Cardiovascular Medications (Toxicity)
  • Angiotensin-converting Enzyme (ACE) Inhibitors
  • Calcium Channel Blockers
  • β Blockers
  • Phenylpropanolamine
  • Diuretics

• Tranquilizers, Antidepressants, Sleep Aids, and Anticonvulsants (Toxicity)
  • Benzodiazepines
  • Antidepressants
    • Selective Serotonin Reuptake Inhibitors:
    • Tricyclic Antidepressants:
    • Monoamine Oxidase Inhibitors:
    • Miscellaneous (Atypical) Antidepressants:
    • Treatment:
    • Serotonin Syndrome:
  • Barbiturates
  • Sleep Aids
  • Phenothiazine Tranquilizers

• Muscle Relaxants (Toxicity)

• Topical Agents (Toxicity)
  • 5-Fluorouracil
  • Calcipotriene

• Prescription Nonsteroidal Anti-inflammatory Drugs (Toxicity)
  • Etodolac
  • Meloxicam
  • Deracoxib
  • Piroxicam
  • Diclofenac
  • Indomethacin
  • Etodolac
  • Nabumetone

• Toxicities from Illicit and Abused Drugs
  • Amphetamines and Related Drugs
    • Pharmacokinetics and Toxicity:
    • Pathogenesis:
    • Clinical Findings and Diagnosis:
    • Treatment:
  • Cocaine
    • Pharmacokinetics and Toxicity:
    • Pathogenesis:
    • Clinical Findings and Diagnosis:
    • Treatment:
  • Ecstasy (MDMA or 3,4-Methylenedioxymethamphetamine)
  • Marijuana
    • Pharmacokinetics and Toxicity:
    • Pathogenesis:
    • Clinical Findings and Diagnosis:
    • Treatment:
  • Opiates
    • Pharmacokinetics and Toxicity:
    • Pathogenesis:
    • Clinical Findings:
    • Diagnosis:
    • Treatment: