Merck Manual

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Canine blood smear, regenerative anemia
Canine blood smear, regenerative anemia

A regenerative anemia with increased polychromasia and acanthocytosis in blood from a dog with hemangiosarcoma. A neutrophil and a nucleated erythrocyte (metarubricyte) are also present (Wright-Giemsa, 100X oil immersion). Acanthocytes are commonly seen in this disorder when metastatic liver infiltrates occur.

Courtesy of Dr. John W. Harvey.