Merck Manual

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Antiemetic Drugs

Antiemetic Drugs

Drug

Dosage

Acepromazine

0.025–0.2 mg/kg, IV, IM, SC, maximum 3 mg; 1–3 mg/kg, PO

Chlorpromazine

0.5 mg/kg, IV, IM, SC, tid-qid

Prochlorperazine

0.1 mg/kg, IM, tid-qid; 1 mg/kg, PO, bid

Aminopentamide

0.022 mg/kg, PO, SC, or IM, bid-tid

Dimenhydrinate

4–8 mg/kg, PO, tid

Diphenhydramine

2–4 mg/kg, PO, tid

Butorphanol

0.2–0.4 mg/kg, IM, once to twice daily

Metoclopramide

0.1–0.5 mg/kg, IM, SC, or PO, tid; 0.01–0.02 mg/kg/hr, IV infusion

Ondansetron

0.1–0.2 mg/kg, PO, once to twice daily; 0.1–0.15 mg/kg, IV, bid-tid

Granisetron

0.5–1 mg/kg, PO, bid; 0.1–0.15 mg/kg, IV, bid-tid

Dolasetron

0.6–1 mg/kg/day, IV

Maropitant

2 mg/kg, PO or 1 mg/kg/day, SC, for up to 5 days (acute vomiting); 8 mg/kg/day, PO, for up to 2 days (motion sickness)