Merck Manual

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Dosages of Antistaphylococcal Antibiotics

Dosages of Antistaphylococcal Antibiotics

Drug

Dosage

Cephalosporins

Cephalexin

20–30 mg/kg, bid, PO

Cephadroxil

Dogs: 20 mg/kg, bid, PO

Cats: 20 mg/kg/day, PO

Cefaclor

10–25 mg/kg, bid, PO

Cefovecin

8 mg/kg, SC, every 14 days

Cefpodoxime

5–10 mg/kg/day, PO

Penicillins

Amoxicillin-clavulanate

13.75 mg/kg, bid, PO

Oxacillin

22 mg/kg, tid, PO

Fluoroquinolones

Enrofloxacin

5 mg/kg/day, PO

Marbofloxacin

2 mg/kg/day, PO

Orbifloxacin

2.5 mg/kg/day, PO

Difloxacin

5 mg/kg/day, PO

Pradofloxacin

3 mg/kg/day, PO

Sulfonamides

Trimethoprim-sulfadiazine

15–30 mg/kg, bid, PO

Trimethoprim-sulfamethoxazole

15–30 mg/kg, bid, PO

Macrolides

Erythromycin

15–30 mg/kg, tid, PO

Clindamycin

Dogs: 10–20 mg/kg, bid, PO

Cats: 12.5–25 mg/kg, bid, PO

Lincomycin

10–20 mg/kg, bid, PO

Azithromycin

10 mg/kg/day, PO

Others

Chloramphenicol

50 mg/kg, tid, PO

Rifampin

5–10 mg/kg, once or twice daily, PO