Merck Manual

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Competitive Nondepolarizing Agents and Antagonists

Competitive Nondepolarizing Agents and Antagonists

Drug

Dosage

Nondepolarizing agents

Tubocurarine chloride

Horses: ≤0.22–0.25 mg/kg , IV

Dogs, cats: ≤0.4 mg/kg, IV

Gallamine triethiodide

All species (except pigs): 0.8–1 mg/kg, IV

Pancuronium bromide

Dogs, cats: 0.6 mg/kg, IV

Alcuronium chloride

Dogs, cats: 0.1 mg/kg, IV

Atracurium besylate

Dogs, cats: 0.5 mg/kg, IV

Antagonists

Neostigmine

0.04 mg/kg, with atropine at 0.04 mg/kg, IV

Pyridostigmine

0.2–0.25 mg/kg, with atropine at 0.04 mg/kg, IV

Edrophonium

0.125 mg/kg, IV