Merck Manual

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Assessment of Regeneration in Anemia

Assessment of Regeneration in Anemia

Signs of Regenerative Anemia

Signs of Nonregenerative Anemia

Reticulocytosis >60,000 or >1%

Reticulocytosis <60,000 or <1%

Macrocytosis (increased MCV)

Microcytosis (decreased MCV)

Nucleated RBCs (nRBC)

Normocytic (normal MCV)

Polychromasia

Lack of response in 3–5 days

Hypochromia (decreased MCHC)

Normochromia (normal MCHC)

MCHC, mean corpuscular hemoglobin concentration; MCV, mean cell volume