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Disruption of ovarian cycle and induced repetitive pseudopregnancy (rats, at high doses)
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Cleft palate, increased fetal mortality (mice)
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Malformations or other developmental toxicity (mice)
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Malformations such as cyclopia and diaphragmatic hernia (rabbits); skeletal variations in rats
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2,4-Da or 2,4,5-Ta alone or in combination
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Malformations such as cleft palate, hydronephrosis; teratogenic (mice, rats)
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Teratogenic (mice); affect postnatal behavior (rats)
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Multiple defects (mice, rabbits)
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Skeletal malformations (rats); skeletal, jaw, head, and visceral (rabbits)
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Malformations (mice only)
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Teratogenic and embryotoxic (rats), teratogenic (mice)
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Head, limbs, and tail defects (rat)
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Slightly teratogenic (rats)
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Malformations (mice, rats, hamsters)
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Malformations/teratogenic (fetotoxicity in chickens, rats, mice, rabbits, guinea pigs, hamsters, and monkeys)
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Malformations such as cleft palate (mice); skeletal variations (rats)
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