Merck Manual

Please confirm that you are a health care professional

Loading

Exertional Myopathy in Small Animals

(Rhabdomyolysis, Tying-up, Monday morning disease)

By

Joseph Harari

, MS, DVM, DACVS, Veterinary Surgical Specialists, Spokane, WA

Last full review/revision May 2013 | Content last modified May 2013

This acute exertional myopathy of racing Greyhounds and working dogs is characterized by muscle ischemia secondary to exercise or excitement. Avascularity and lactic acidosis cause muscular lysis, myoglobin release, and a nephropathy.

Clinical signs include muscle pain and swelling 24–72 hr after racing. Severe cases are characterized by stiffness, hyperpnea, collapse, myoglobinemia, and acute renal failure. Urinalysis reveals myoglobinuria; serum potassium, phosphorus, and muscle enzymes are increased. Treatment includes supportive care such as IV fluids, bicarbonate, body cooling, rest, and muscle relaxants (eg, diazepam). Prognosis depends on severity. (Also see Exertional Myopathies in Horses.)

Others also read

Also of Interest

SOCIAL MEDIA

TOP