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Formalin (Parasite-S®, Formalin-F™, Formacide-B)
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Control external protozoa (Chilodonella, Ichthyobodo, Epistylis, Ichthyophthirius, Ambiphyra, Trichodina spp), Tetrahymena spp and monogeneans (Cleidodiscus, Dactylogyrus, Gyrodactylus spp)
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Tanks and raceways: salmon and trout: above 50°F: up to 170 μL/L for up to 1 hr; below 50°F: up to 250 μL/L for up to 1 hr. All other finfish: up to 250 μL/L for up to 1 hr
Earthen ponds: 15–25 μL/L indefinitely
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Drug must not be subjected to temperature <40°F. Do not apply to ponds when water is warmer than 80°F, there is a heavy phytoplankton bloom, or dissolved oxygen is <5 mg/L. Ponds may be re-treated in 5–10 days if needed. Do not treat ponds containing striped bass. Test on a small number from each lot to check for any unusual sensitivity to formalin before proceeding.
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Control water molds of the family Saprolegniaceae
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All finfish eggs: 1,000–2,000 ppm for 15 min; Acipenseriformes: up to 1,500 ppm for 15 min
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Preliminary bioassay should be conducted to determine species sensitivity.
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Control protozoan parasites (Bodo, Epistylis, and Zoothamnium spp )
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Tanks and raceways: 50–100 μL/L for up to 4 hr daily
Earthen ponds: 25 μL/L as single treatment
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Drug must not be subjected to temperature <40°F. Do not apply to ponds when water is warmer than 80°F, when there is a heavy phytoplankton bloom, or when dissolved oxygen is <5 mg/L. Ponds may be re-treated in 5–10 days if needed.
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Hydrogen peroxide (35% PEROX-AID®)
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Freshwater-reared finfish eggs
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Control mortality due to saprolegniasis
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Coldwater and coolwater: 500–1,000 mg/L for 15 min in a continuous flow system daily on consecutive or alternate days until hatch
Warmwater: 750–1,000 mg/L for 15 min in a continuous flow system daily on consecutive or alternative days until hatch
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Initial bioassay on a small number is recommended before treating entire group.
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Freshwater-reared salmonids
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Control mortality due to bacterial gill disease (Flavobacterium branchiophilum)
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100 mg/L (30 min) or 50–100 mg/L (60 min) daily on alternate days for 3 treatments
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Initial bioassay on a small number is recommended before treating entire group.
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Freshwater-reared coolwater finfish and channel catfish
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Control mortality due to external columnaris disease (Flavobacterium columnare)
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Fingerling and adults (except northern pike and paddlefish): 50–75 mg/L (60 min) daily on alternate days for 3 treatments
Fry (except northern pike, pallid sturgeon, and paddlefish): 50 mg/L (60 min) daily on alternate days for 3 treatments
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Use with caution on walleye.
Initial bioassay on a small number is recommended before treating entire group.
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Oxytetracycline hydrochloride (OxyMarine, Oxytetracycline HCI Soluble Powder-343®, Terramycin-343 Soluble Powder, PENNOX 343, TETROXY Aquatic)
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Finfish fry and fingerlings
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Mark skeletal tissues, most often otoliths, of finfish fry and fingerlings for identification purposes
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200–700 mg oxytetracycline hydrochloride (buffered) per liter of water for 2–6 hr
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Tricaine methanesulfonate (Tricaine-S®)
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Fish, amphibians, and other aquatic poikilotherms
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1:1,000 to 1:20,000 (other poikilotherms)
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Powder is added to water; concentration depends on desired degree of anesthesia, species, size, water temperature and softness, stage of development.
Preliminary tests of solution should be made with a few fish; 21-day withdrawal time (fish); laboratory or hatchery use only in other poikilotherms; water temperature >50°F (10°C)
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Chorionic gonadotropin (Chorulon®)
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Male and female brood finfish
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Help improve spawning function
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50–510 IU/lb males; 67–1,816 IU/lb females
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IM injection up to 3 doses; total dose not to exceed 25,000 IU in fish intended for human consumption; restricted to use by or on the order of a licensed veterinarian
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Freshwater-reared finfish
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Control of mortality due to enteric septicemia of catfish associated with Edwardsiella ictaluri, streptococcal septicemia in freshwater-reared warmwater finfish, columnaris disease in freshwater-reared finfish
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10 mg/kg/day for 10 consecutive days
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Veterinary Feed Directive drug; 12-day withdrawal time
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Oxytetracycline dihydrate (Terramycin-200® for Fish)
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Mark skeletal tissue, most often otoliths, of finfish fry and fingerlings for identification purposes
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Salmon <30 g; in feed as sole ration; 7-day withdrawal time
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Freshwater-reared salmonids
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Bacterial coldwater disease (Flavobacterium psychrophilum)
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2.5–3.75 g/100 lb/day for 10 days
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In mixed ration; water temperature not <48.2°F; 21-day withdrawal time
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Scaled warm freshwater-reared finfish
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Control bacterial hemorrhagic septicemia (Aeromonas liquefaciens) and pseudomonas disease (Pseudomonas)
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Cool freshwater-reared finfish
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Control bacterial hemorrhagic septicemia (Aeromonas liquefaciens, furunculosis (Aeromonas salmonicida), and pseudomonas disease (Pseudomonas)
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2.5–3.75 g/100 lb/day for 10 days
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In mixed ration; water temperature not <62°F; 21-day withdrawal time
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Control gaffkemia (Aeroccocus viridans)
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1 g/lb medicated feed for 5 days
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In feed as sole ration; 30-day withdrawal time
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All freshwater-reared finfish
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Control of columnaris disease
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Sulfadimethoxine-ormetoprim (Romet-30®)
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Control furunculosis (Aeromonas salmonicida)
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In feed; 42-day withdrawal time
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Control enteric septicemia (Edwardsiella ictaluri)
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In feed; 3-day withdrawal time
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Rainbow, brook, and brown trout
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Control furunculosis (Aeromonas salmonicida)
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10 g/100 lb/day for up to 14 days
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In feed; 21-day withdrawal time; not currently available
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