Table: Dosages of Antiviral Drugs - Merck Veterinary Manual

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Dosages of Antiviral Drugs

Drug	Preparation	Dose, Route, and Frequency	Indication
Idoxuridine	0.1% ophthalmic solution	1 drop, topical, every 5–6 hr
	0.5% ophthalmic solution	1 drop, topical, every 1–2 hr
Trifluridine	1% ophthalmic solution	1 drop, topical, every 2 hr initially (2 days), then 3–8 times daily	Ocular herpesvirus infection
Vidarabine	3% ophthalmic solution	0.4–1 cm ointment, topical, every 5–6 hr; 3–6 times daily	Ocular herpesvirus infection
	200 mg/mL suspension for injection	10–30 mg/kg/day, IV, as CRI for 12–24 hr
Acyclovir	200-mg capsules or tablets	200 mg, PO, qid, every 4 hr, or 5 times daily	Feline herpesvirus
	5% cutaneous ointment	Cover lesion, topical, every 3 hr, 6 times daily
	200 mg/5 mL suspension	80 mg/kg/day (mixed with peanut butter), PO, for 7–14 days	Pacheco’s disease in birds
	500 mg/vial powder	250–500 mg/m², IV, tid, infused over at least 1 hr
Ganciclovir	500 mg/vial powder	2–5 mg/kg, IV, bid-tid
Ribavirin		11 mg/kg/day, IV, for 7 days	Susceptible viral infections
	6 g/100 mL vial powder	Using SPAC-2 nebulizer only, inhalation, 8–18 hr period daily
Zidovudine	10 mg/mL syrup; 10 mg/mL injection	5–20 mg/kg (cats), PO or SC, bid-tid	FIV, FeLV
Amantadine	100- and 500-mg capsules	100 mg total (human), PO, once to twice daily
	Syrup 10 mg/mL	100 mg/day total (juveniles), PO
Rimantadine		200–300 mg/day total (human), PO
Interferon α-2	3 × 10⁶ IU/vial	3 × 10⁶ IU/person/day, SC, IM; 0.5–5 U/kg/day, PO; 100,000 U/kg/day, SC	FeLV-associated disease
		1 U/day, PO	FeLV appetite stimulant
		15–30 U, PO, IM, SC, once daily on alternate weeks	FIP, FIV
CRI = constant-rate infusion; FeLV = feline leukemia virus; FIP = feline infectious peritonitis; FIV = feline immunodeficiency virus

Merck Manual

Dosages of Antiviral Drugs