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---------------Diagnosis (Test Utility)---------------
Clinical Signs
Prevention
-----Treatment-----
Microfilaria
Ag or Ab Test
Thoracic Radiographs
Echocardiography
Adults
Microfilariae
Dog
****
***** (Ag)
***
MPA, PA, RHE, PTE, PIE
**
Respiratory, weight loss, exercise intolerance
Ivermectin, milbemycin, selamectin, moxidectin
Melarsomine, doxycycline, symptomatic treatment
Moxidectina, ivermectin + doxycycline, milbemycin
Cat
*
** (Ag)
**** (Ab)
PA, PIE
Respiratory, vomiting, sudden death
Symptomatic treatment, worm extraction
NA
Ferret
*** (Ag)
RH
Heart failure, respiratory, sudden death
Topical imidacloprid-moxidectin
Symptomatic treatment, moxidectin?
aImidacloprid-moxidectin is the only approved microfilaricide.
* = rarely useful; ** = somewhat useful; *** = moderately useful; **** = often useful; ***** = excellent test; Ag = antigen; Ab = antibody; MPA = main pulmonary artery enlargement; PA = pulmonary artery enlargement; PTE = pulmonary thrombus/thromboembolus; PIE = pulmonary infiltrate with eosinophils; RH = right heart enlargement; NA = not applicable
Adapted from McCall, JW. Clin Tech Small Anim Pract. 1998;13(2):112.