Drugs Used in Aquaculture in the USA – Approval Status and Withdrawal Times
|
Active Ingredient |
Trade Name |
Generic Use |
Application Method |
Approval Statusa |
Withdrawal Time |
|
Florfenicol |
Aquaflor® |
Antibiotic |
Medicated feed |
FDA approveda (Veterinary Feed Directive) |
15 days |
|
Oxytetracycline dihydrate |
Terramycin-200® |
Antibiotic |
Medicated feed |
FDA approved |
21 days |
|
Ormetoprim sulfadimethoxine |
Romet-30® |
Antibiotic |
Medicated feed |
FDA approved |
42 days in salmonids; 3 days in catfish |
|
Hydrogen peroxide (35%) |
PEROX-AID® |
Antimicrobial (gills and skin only) |
Immersion |
FDA approved |
None |
|
Chloramine-T |
HALAMID Aqua® |
Antimicrobial (gills and skin only) |
Immersion |
FDA approved |
None |
|
Diquat |
Reward® |
Herbicide Antibiotic (gills and skin only) |
Immersion Immersion |
EPA INAD required |
5 days in channel catfish, muskellunge, tiger muskellunge, northern pike; 30 days in all others |
|
Formalin |
Formalin-FTM Formalin-B Parasite-S® |
Parasiticide (gills and skin only) |
Immersion |
FDA approved |
None |
|
Copper sulfate (CuSO4) |
|
Parasiticide (gills and skin only) |
Immersion |
INAD required |
7 days |
|
Potassium permanganate (KMnO4) |
|
Parasiticide (gills and skin only) |
Immersion |
INAD required |
7 days |
|
Diflubenzuron |
Dimilin® |
Parasiticide (external crustaceans) |
Immersion |
EPAa (restricted use pesticide) |
Not for use in food fish |
|
Tricaine methanesulfonate |
Tricaine-S® |
Anesthetic |
Immersion |
FDA approved |
21 days |
|
Eugenol |
Aqui-S20E® |
Anesthetic |
Immersion |
INAD required |
72 hours |
|
Metomidate |
Aquacalm® |
Sedative |
Immersion |
The Index |
Not for use in food fish |
|
Chorionic gonadotropin |
Chorulon® |
Spawning aid |
Injection |
FDA approveda (prescription only) |
None (broodstock) |
|
sGnRHa + domperidone |
Ovaprim® |
Spawning aid |
Injection |
The Index |
Not for use in food fish |
|
a Approval status is of January 8, 2015. Practitioners should check the FDA Web site (www.fda.gov/AnimalVeterinary/ResourcesforYou/AnimalHealthLiteracy/ucm213944.htm) frequently for the most current information. |
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