Merck Manual

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Prokinetic Drugs

Prokinetic Drugs

Drug

Dosage

Metoclopramide

Dogs and cats: 0.2–0.5 mg/kg, PO or SC, tid; 0.01–0.02 mg/kg/hr, IV infusion

Horses: 0.125–0.25 mg/kg, diluted in 500 mL of polyionic solution and administered IV over 60 min

Domperidone

0.1–0.5 mg/kg, IM; 0.5–1 mg/kg, PO

Cisapride

Dogs: 0.1 mg/kg, PO, tid

Cats: 2.5 mg/cat, tid for cats <5 kg, and 5 mg/cat for cats >5 kg

Erythromycin

0.5–1 mg/kg, PO, bid-tid

Ranitidine

1–2 mg/kg, PO, bid

Nitazidine

2.5–5 mg/kg, PO, bid

Lidocaine

Horses: 1.3 mg/kg, IV, as a bolus followed by a constant-rate infusion of 0.05 mg/kg/min