Merck Manual

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Vaccine Recommendations for Nonhuman Primates

Vaccine Recommendations for Nonhuman Primates

Group

Vaccine

Dosage

Comments

Prosimians (lemurs, lorises, galagos)

Tetanus (adsorbed human product or equine product

0.5 mL, IM, every 5 years. (If less than 1 kg, 0.1-0.25 mL)

Rabies (killed vaccine)

1.0 mL, IM or SC, annually

Callitrichids (marmosets and tamarins)

Tetanus (Same products as prosimians)

0.1 mL, IM, every 5 years

Rabies (killed vaccine)

1.0 mL, SC, annually

Only if there is a risk of exposure in the facility.

Measles (canine distemper-measles vaccine)

Modified live vaccine may cause disease and is NOT recommended. Recent studies with canarypox-vector vaccines show active titers. If there is high risk of exposure can be considered for off-label use.

Cebidae (spider, capuchin, and squirrel monkeys)

Tetanus (same products as other species)

0.5 mL, IM, every 5 years

Rabies (killed vaccine)

1.0 mL, IM or SC, annually

Only if there is risk of exposure in the facility.

Measles

Modified live vaccine may cause disease and is NOT recommended.

Cercopithecidae (macaques, drills, mangabeys, guenons, baboons)

Tetanus (same products as for other species)

0.5 mL, IM, every 5 years

Rabies (killed vaccine)

1.0 mL, IM or SC, annually

Doses should be given at 4–6 months old, then at 1 year old, then annually.

Measles (MMR vaccine, for macaques)

0.5 mL, SC

First dose at >6 months old, booster in 6 months, then at 6–7 years. Do not vaccinate pregnant animals.

Apes (gibbons and siamangs)

Tetanus (same products as for other species)

0.5 mL, IM, every 5 years

Rabies (killed vaccine)

1.0 mL, IM or SC, annually

Measles (MMR vaccine)

IM

First dose at 4–6 months old, booster in 6 months, then at 6–7 years. Do not vaccinate pregnant animals. This vaccine may lead to a false-positive intradermal TB test.

Great apes (orangutans, chimpanzees, gorillas)

Tetanus (human adsorbed product)

0.5 mL, IM, every 5 years

Alternative: diphtheria pertussis tetanus (DPT) vaccine at 10-year intervals

Rabies (killed vaccine)

1.0 mL, IM or SC, annually

First dose after 6 months old

Polio (inactivated, injectable vaccine)

IM, at 1–2 years old

Pneumococcus

As needed for geriatric patients

Respiratory syncitial virus

Not routine