Merck Manual

Please confirm that you are a health care professional

Inherited Cataracts in Domestic Animals

Inherited Cataracts in Domestic Animals

Breed

Age of Onset

Initial Localization

Mode of Inheritance

Dogs

Afghan Hound

6–12 mo

Equatorial/posterior cortex

Autosomal recessive

American Cocker Spaniel

1–6 yr

Posterior/anterior cortex

Autosomal recessive polygenetic

Australian Shepherd

2–4 yr

Posterior cortex

Autosomal dominanta

Bichon Frise

2–6 yr

Posterior/anterior cortex

Autosomal recessive

Boston Terrier

Congenital or juvenile

Late onset

Posterior sutures/nuclear

Equatorial/anterior cortex

Autosomal recessivea

Autosomal recessive

Chesapeake Bay Retriever

≥1 yr

Nuclear/cortex

Incomplete dominant

Entelbucher Mountain Dog

1–2 yr

Posterior cortex

Autosomal recessive

German Shepherd

≥8 wk

Posterior sutures/ cortex

Incomplete dominant

Golden Retriever

≥6 mo

Posterior subcapsular (triangular)

Incomplete dominant

Labrador Retriever

≥6 mo

Posterior subcapsular (triangular)

Incomplete dominant

Havanese

2–6 yr

Posterior/anterior cortex

Possible autosomal recessive

Miniature Schnauzer

Congenital

≥6 mo

Nuclear/posterior cortex

Posterior cortex

Autosomal recessive

Autosomal recessive

Norwegian Buhund

≥1 yr

Nuclear/cortex

Autosomal dominant

Old English Sheepdog

Congenital

Nuclear/cortex

Autosomal recessive

Rottweiler

≥10 mo

Posterior polar/complete

Unknown

Siberian Husky

≥6 mo

Posterior subcapsular/ posterior sutures

Autosomal recessive

Staffordshire Bull Terrier

≥6 mo

Posterior sutures/ cortex

Autosomal recessivea

Standard Poodle

≥1 yr

Equatorial cortex

Autosomal recessive

Welsh Springer Spaniel

Congenital

Nuclear/posterior cortex

Autosomal recessive

West Highland White Terrier

Congenital

Posterior sutures

Autosomal recessive

Horses

Belgian

Congenital

Nuclear/cortex

Autosomal dominant

Morgan

Congenital

Nuclear

Autosomal dominant

Cattle

Holstein-Friesian

Congenital

Nuclear/cortex

Autosomal recessive

Jersey

Congenital

Nuclear

Autosomal recessive

Sheep

New Zealand Romney

Congenital

Anterior/posterior cortex

Autosomal dominant

a Associated with mutations in HSF4 gene.