Merck Manual

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Synthetic Colloids

Synthetic Colloids

Colloid

In Solution with

Average Molecular Weight (daltons)

Average (and Range of) Molecular Weight (daltons)

C2:C6 Ratio

Colloid Oncotic Pressure (mmHg)

Suggested Upper Limit (dose/kg/day)

Concentration (%)

Dextran 70

0.9% NaCl

70,000

10,000–80,000

NA

59

20 mL

6

HextendTM

(670/0.7)

x

Lactated electrolyte solution

670,000

20,000–2,500,000

5:1

25–30

20 mL

6

VetStarchTM/VoluvenTM

(130/0.4)

0.9% saline

130,000

110,000–150,000

9:1

36

50 mL

6

HESPAN®

(600/0.4)

0.9% saline

600,000

450,000–800,000

5:1

25–30

20 mL

6

Stroma-free hemoglobin (Oxyglobin®)

Modified lactated Ringer's solution

65,000–130,000

Up to 500,000

NA

20

See text

13

NA = not applicable