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Tetracycline
Species
Elimination Half-life (hr)
Volume of Distribution (mL/kg)
Clearance (mL/kg/min)
Oxytetracycline
Dogs
6
3,000
4.23
Calves (<3 mo old)
10–13
1,500–2,400
3.45
Cattle
7–10
800–1,000
3.33
Horses
8–10
1,100
2.89
Minocycline
7
2,000
3.21
Doxycycline
930
1.7
Cats
5
340
1.0
9