Merck Manual

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Elimination and Distribution of Chloramphenicol and Florfenicol

Elimination and Distribution of Chloramphenicol and Florfenicol

Drug

Species

Elimination Half-life (hr)

Volume of Distribution (mL/kg)

Chloramphenicol

Cats

5.1

2,360

Dogs

4.2

1,700

Calves (<1 wk old)

5.0

1,080

Cattle

3.0

1,580

Horses

0.9

950

Florfenicol

Cattle

18.3

700