Table: Poisonous Mushrooms: Onset of Action and Organs Targeted

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Poisonous Mushrooms: Onset of Action and Organs Targeted

Mushrooms	Toxin	Onset Time	Organ/System


*Latent Period >6 hr After Ingestion; Life-threatening*
Amanita phalloides; A virosa	Cyclopeptides, α and β amanitins, phallotoxins, virotoxins	6–24 hr, rarely >24 hr	Primarily liver, kidney secondary
Conocybe filaris	α and β amanitins	6–14 hr, rarely >24 hr	Primarily liver
Cortinarius gentilis	Orellanin, orelline	3–14 days (days/weeks)	Primarily renal^a
Galerina autumnalis; G venenata	α and β amanitins	6–14 hr, rarely >24 hr	Primarily liver
Gyromitra esculenta	Monomethylhydrazine	6–24 hr	CNS
Lepiota spp	α and β amanitins	6–14 hr, rarely >24 hr	Primarily liver


*Latent Period ≤3 hr After Ingestion; Not Life-threatening*
Amanita muscaria; A pantherina	Isoxazoles: ibotenic acid muscimol	30 min–2 hr; recovery 4–24 hr	CNS
Chlorophyllum molybdites	Unknown	30 min–3 hr; recovery 1–2 days	GI
Clitocybe dealbata; Clitocybe spp; Inocybe spp	Muscarine	30 min–2 hr; recovery 6–24 hr	Autonomic nervous system
Paxillus involutus	Unknown	1–3 hr; recovery 2–4 days	Immune system
Psilocybe spp; Conocybe smithii; Gymnopilus spectabilis; Panaeolus subbalteatus	Psilocybin and psilocin	30–60 min; rarely 6 hr	CNS
Russula emetica	Unknown	30 min–3 hr; recovery 1–2 days	GI
^a No reported veterinary cases

Merck Manual