Table: Drugs for Intestinal Helminths of Cats Approved in the USA and UK

Veterinary /

StandaloneMedia /

Drugs for Intestinal Helminths of Cats Approved in the USA and UK

Drug or Drug Combination	Dosage (mg/kg)	Route of Administration	Helminths Active Against^a
*Approved only in USA*
Epsiprantel	2.75	PO	Dipylidium caninum, Taenia taeniaeformis
Ivermectin	0.024	PO	Ancylostoma tubaeforme, A braziliense
Milbemycin oxime	2	PO	Toxocara cati, A tubaeforme
Piperazine (various salts)	48–88^{b, d}	PO	T cati^c, Toxascaris leonina
Praziquantel	4.6–10	PO	D caninum, T taeniaeformis
	5–10	SC, IM	D caninum, T taeniaeformis
Praziquantel + pyrantel pamoate	5/20	PO	T cati, A tubaeforme, D caninum, T taeniaeformis

*Approved only in UK*
Fenbendazole	50, daily for 3 days; 100	PO	T cati, T leonina, Ancylostoma spp, Uncinaria spp, Taenia spp
Praziquantel	5	PO	D caninum, T taeniaeformis, Echinococcus multilocularis^c
	8	Topical	D caninum, Taenia spp, E multilocularis
Milbemycin oxime + praziquantel	2/5	PO	T cati, A tubaeforme, D caninum, Taenia spp, E multilocularis
Praziquantel + pyrantel embonate	5/57.5	PO	T cati, T leonina, D caninum, T taeniaeformis

*Approved in both USA and UK*
Emodepside + praziquantel	3/12	Topical	T cati, A tubaeforme, D caninum, T taeniaeformis, T leonina^d, E multilocularis^d
Moxidectin + imidacloprid	1/10	Topical	T cati, A tubaeforme
Selamectin	6	Topical	T cati, A tubaeforme
^a Many of these drugs are also approved for use against other types of parasites (eg, fleas, heartworms) not listed here.
^b Repeat in 10–14 days for most products
^c Only some products
^d Only in the USA

Merck Manual