Dose and Route
1–5 mg/kg, IM, SC, every 24 hours
10 mg/kg, IM, SC
Chelonians (red-eared sliders)
Lizards (bearded dragons)
Not analgesic for snakes. Causes pronounced respiratory depression in turtles.
0.5 mg/kg, IM, SC
Chelonians: appears to cause less respiratory depression than morphine
5–10 mg/kg, PO, every 2–3 days
Chelonians (red-eared sliders); less respiratory depression than morphine
0.1–0.4 mg/kg, IV, IM, SC, every 24–48 hours
10–25 mg/kg, combined with dexmedetomidine 0.05–0.1 mg/kg and hydromorphone 0.5 mg/kg, IM (or 50% dose, IV)
Deep sedation/anesthesia in many chelonians. Reversed using atipamezole (0.5 mg/kg, IM) and, if necessary, naloxone (0.1 mg/kg, IM)
1–2 mg/kg, IM
3–12 mg/kg, IM
Tortoises, lizards, snakes. Low dose useful to facilitate intubation. Higher doses associated with prolonged recoveries.
3–10 mg/kg, IV, intraosseous
Low dose rate for larger reptiles. Subanesthetic doses produce variable short-term sedation.
5–10 mg/kg, IV
10–20 mg/kg, IM
Similar effects to those of propofol IV, but higher doses effective IM. Larger IM dose volumes necessitate dividing into two or more injections.
Routine gaseous agent; subanesthetic levels provide short-term sedation. Mask down or conscious (sedated) intubation possible in some species.
Very similar effects to those of isoflurane but recoveries appear to be faster. Preferred agent for critical or large reptiles.