Not Found
Locations

Find information on animal health topics, written for the veterinary professional.

Platelets of Dogs

By Peter H. Holmes, BVMS, PhD, Dr HC, FRCVS, FRSE, OBE, Emeritus Professor and Former Vice-Principal, Faculty of Veterinary Medicine, University of Glasgow ; Nemi C. Jain, MVSc, PhD, Professor Emeritus of Clinical Pathology, Department of Veterinary Pathology, Microbiology, and Immunology, School of Veterinary Medicine. University of California ; David J. Waltisbuhl, BASc, MSc, Senior Scientist DPI&F Actest, Yeerongpilly Veterinary Laboratory ; Michael Bernstein, DVM, DACVIM, Director, Medical Services, Angell Animal Medical Center ; Karen L. Campbell, MS, DVM, DACVIM, DACVD, Professor and Section Head, Specialty Medicine, Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois ; Timothy M. Fan, DVM, PhD, DACVIM, Associate Professor, Department of Veterinary Clinical Medicine, University of Illinois ; Wayne K. Jorgensen, BSc, PhD, Science Leader Applied Biotechnology Livestock, Agri-Science Queensland ; Susan L. Payne, PhD, Associate Professor, Department of Veterinary Pathobiology, Texas A&M University

Platelets are small, cell-like particles produced in the bone marrow. They function to start the formation of blood clots. Platelets gather where bleeding occurs and clump together to form the initial plug that stops or slows the flow of blood. Platelets also release substances that are needed to complete the clotting process.

Platelet disorders can result from having too few or too many platelets or from impaired platelet function. In general, when platelet counts fall very low there is an increased risk of bleeding. Decreased numbers of platelets may be caused by autoantibodies, drugs, toxins, or disorders of the bone marrow.

An abnormal increase in the number of platelets is rare and often the cause is not known. It may be associated with bone marrow disease or with longterm blood loss and iron deficiency.

There are also disorders in which platelets do not function properly. Von Willebrand disease is one example. Other hereditary disorders of platelet function have been described but are rare. Probably the most common platelet function defect in animals is a side effect of aspirin. Do not give your dog aspirin—or any other medication—unless it is prescribed by your veterinarian.