Merck Manual

Please confirm that you are a health care professional

honeypot link
Drug-receptor binding dose-response curve
drug-action-ferguson-figure-3-sized
Drug-receptor binding dose-response curve

    Dose-response curve for drug-receptor binding showing receptor occupancy vs drug concentration (on a logarithmic scale). Mass action of binding predicts a nonlinear dose-response curve, which is hyperbolic but often shown as a sigmoidal plot. Bmax = Maximal binding capacity.

Courtesy of Dr. Duncan C. Ferguson.