Effect of non-competitive antagonist on dose-response relationship
Effect of non-competitive antagonist on dose-response relationship
Dose-response curve for an agonist drug with and without the presence of a noncompetitive (NC) antagonist. In the presence of a noncompetitive antagonist, the apparent maximal effect (Emax) of an agonist is decreased (indicated by arrows).
Courtesy of Dr. Duncan C. Ferguson.
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