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Kupffer cell activation, photomicrograph, dog
kupffer-cell-hypertrophy-biopsy-center-sized
Kupffer cell activation, photomicrograph, dog

    Photomicrograph of liver biopsy from a dog demonstrates Kupffer cell activation, hypertrophy, and marked phagocytosis of sinusoidal fluxing cellular and particulate debris. Enlarged Kupffer cell profiles (black arrows) and cellular debris partially compromise transhepatic perfusion. H&E stain; scale bar = 60 mcm.

Courtesy of Dr. Sharon Center.