Dosages of Penicillins
Dosages of Penicillins
Penicillin | Dosage, Route, and Frequency |
|---|---|
Sodium penicillin G | 10,000–20,000 IU/kg, IV or IM, qid |
Potassium penicillin G | 25,000 IU/kg, PO, qid |
Procaine penicillin G | 10,000–30,000 IU/kg, IM or SC, once to twice daily |
Benzathine penicillin G | 10,000–40,000 IU/kg, IM (horses) or SC (cattle), every 48–72 hr |
Penicillin V | 15,000 IU/kg or 8–10 mg/kg, PO, tid-qid |
Cloxacillin | 10–25 mg/kg, IM or PO, qid |
Ampicillin | 5–10 mg/kg, IV, IM, or SC, bid-tid; 10–25 mg/kg, PO, bid-qid |
Amoxicillin | 4–10 mg/kg, IM, once to twice daily; 10–20 mg/kg, PO, bid-qid (dogs) |
Sodium carbenicillin | 10–20 mg/kg, IV or IM, bid-qid |
Potassium clavulanate:amoxicillin (1:4) | 10–20 mg/kg (amoxicillin) and 2.5–5 mg/kg (clavulanate), PO, bid-qid |
Probenecid (prolongs blood concentrations of penicillins that have short plasma half-lives or that are costly) | 1–2 mg/1,000 IU penicillin G (dogs), PO, qid |
Amoxicillin-clavulanic acid | 10–20 mg/kg, PO, bid-qid |
Imepenem | 1–7 mg/kg, IV or IM, bid-tid |
Meropenem | 12–24 mg/kg, IV or SC, bid-tid |
Ticarcillin (with or without clavulanic acid) | 40–110 mg/kg, IM or IV, tid-qid |