Elimination and Distribution of Chloramphenicol and Florfenicol
Elimination and Distribution of Chloramphenicol and Florfenicol
Drug | Species | Route | Elimination Half-life (h) | Volume of Distribution (L/kg) | Clearance (mL/kg/min) |
|---|---|---|---|---|---|
Chloramphenicol | Cats | IV | 5.1 | 2.36 | |
Dogs | IV | 4.2 | 1.7 | ||
Goats | IV | 4.0 | 0.77 | 2.5 | |
Cattle | IV | 4.25 | 1.58 | 7.2 | |
Horses | IV | 1.35 | 0.66 | 17.2 | |
Florfenicol | Cattle | IV | 3.0 | 0.35 | 2.7 |
Goats | IV | 1.2 | 0.57 | 4.5 | |
Llamas | IV | 2.2 | 0.74 | 4.6 |