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Elimination and Distribution of Chloramphenicol and Florfenicol

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Drug	Species	Route	Elimination Half-life (h)	Volume of Distribution (L/kg)	Clearance (mL/kg/min)
Chloramphenicol	Cats	IV	5.1	2.36
	Dogs	IV	4.2	1.7
	Goats	IV	4.0	0.77	2.5
	Cattle	IV	4.25	1.58	7.2
	Horses	IV	1.35	0.66	17.2
Florfenicol	Cattle	IV	3.0	0.35	2.7
	Goats	IV	1.2	0.57	4.5
	Llamas	IV	2.2	0.74	4.6