Insect Growth Regulators and Insect Development Inhibitors
Drug | Mechanism of Action | Route of Administration | Frequency | Species |
|---|---|---|---|---|
Insect Growth Regulators | ||||
S-Methoprenea | Larvicidal, ovicidal | Topical | q 30 d | Dog, cat |
Pyriproxyfenb | Ovicidal; prevents larvae from pupating | Topical | q 30 d | Dog, cat |
Insect Development Inhibitors | ||||
Lufenuronc,d | Disrupts normal chitin production | Oral | q 30 d | Dog |
aYoung DR, Jeannin PC, Boeckh A. Efficacy of fipronil/(S)-methoprene combination spot-on for dogs against shed eggs, emerging and existing adult cat fleas (Ctenocephalides felis, Bouché). Vet Parasitol. 2004;125(3-4):397-407. doi:10.1016/j.vetpar.2004.07.021 bMeola R, Meier K, Dean S, Bhaskaran G. Effect of pyriproxyfen in the blood diet of cat fleas on adult survival, egg viability, and larval development. J Med Entomol. 2000;37(4):503-506. doi:10.1603/0022-2585-37.4.503 cBlagburn BL, Vaughan JL, Lindsay DS, Tebbitt GL. Efficacy dosage titration of lufenuron against developmental stages of fleas (Ctenocephalides felis felis) in cats. Am J Vet Res. 1994;55(1):98-101. doi:10.2460/ajvr.1994.55.01.98 dHink WF, Zakson M, Barnett S. Evaluation of a single oral dose of lufenuron to control flea infestations in dogs. Am J Vet Res. 1994;55(6):822-824. doi:10.2460/ajvr.1994.55.06.822 | ||||