Relative Potencies of Commonly Used Corticosteroids
Compound | Relative Glucocorticoid Activity | Relative Mineralocorticoid Activity | Duration of Effecta (Alcohol Form) |
|---|---|---|---|
Cortisol | 1 | 1 | S |
Prednisone | 5 | 0.8 | I |
Prednisolone | 5 | 0.8 | I |
Methylprednisolone | 5 | 0.5 | I |
Fludrocortisone | 10 | 125 | I |
Triamcinolone | 5 | 0 | I |
Triamcinolone acetonide | 30 | 0 | I |
Isoflupredone | 25 | 25 | L |
Dexamethasone | 25 | 0 | L |
Betamethasone | 25 | 0 | L |
Flumethasone | 120 | 0 | L |
a S = short (~12 hours), I = intermediate (~24 hours), L = long (~48–72 hours) | |||