By
Frederic J. Hoerr, DVM, PhD, Veterinary Diagnostic Pathology, LLC
Cyclopiazonic acid is a metabolite of Aspergillus flavus, which is the predominant producer of aflatoxin in feeds and grains. In chickens, cyclopiazonic acid causes impaired feed conversion, decreased weight gain, and mortality with lesions forming in the proventriculus, gizzard, liver, and spleen. The proventriculus is dilated, and the mucosa is thickened and variably ulcerated.
Merck & Co., Inc., Rahway, NJ, USA (known as MSD outside of the US and Canada) is dedicated to using the power of leading-edge science to save and improve lives around the world. The Merck Veterinary Manual was first published in 1955 as a service to the community. The legacy of this great resource continues as the Merck Veterinary Manual in the US and Canada and the MSD Vet Manual outside of North America.
