Merck Manual

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Professional Version

Fasciola gigantica in Ruminants

(Giant Liver Fluke)

By

Lora Rickard Ballweber

, DVM, DACVM, DEVPC, Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University

Reviewed/Revised Nov 2021 | Modified Oct 2022

Fasciola gigantica is similar in shape to F hepatica but is longer (75 mm), with less clearly defined shoulders, and is 12 mm wide. It is found in warmer climates (Asia, Africa) in cattle and buffalo, in which it is responsible for chronic fascioliasis, and in sheep, in which the disease is frequently acute and fatal. The life cycle is similar to that of F hepatica, except most parasitic phases are longer, the prepatent period is 10–16 weeks, and the species of snail intermediate hosts are different. An entire life cycle takes at least 20 weeks. The pathology of infection, diagnostic procedures, and control measures are similar to those for F hepatica ( see Fasciola hepatica in Ruminants Fasciola hepatica in Ruminants Fasciola hepatica is one of the most important flukes of domestic ruminants worldwide, causing liver fluke disease (liver rot, fascioliasis). Chronic liver fluke disease is more common... read more <i >Fasciola hepatica</i> in Ruminants ).

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