Merck Manual

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Professional Version

Cloning of Domestic Animals

By

Katrin Hinrichs

, DVM, PhD, DACT, School of Veterinary Medicine, University of Pennsylvania

Last full review/revision Aug 2020 | Content last modified Oct 2020

The basic concept of cloning via nuclear transfer is that the nucleus of a cell, taken from a tissue sample of a donor individual, is transferred to an enucleated oocyte, and then the oocyte is stimulated to develop into an embryo. The embryo thus produced has the same genotype as the original donor individual.

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