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Cloning of Domestic Animals

By

Katrin Hinrichs

, DVM, PhD, University of Pennsylvania School of Veterinary Medicine

Last full review/revision Aug 2020 | Content last modified Oct 2020

The basic concept of cloning via nuclear transfer is that the nucleus of a cell, taken from a tissue sample of a donor individual, is transferred to an enucleated oocyte, and then the oocyte is stimulated to develop into an embryo. The embryo thus produced has the same genotype as the original donor individual.

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Management of the Neonate
Large animal neonates are born immunocompetent but lack antibodies. In their first few hours of life, neonates must suckle good quality colostrum from the dam to obtain maternal antibodies (immunoglobulins). Which of the following factors might compromise the quality of colostrum?
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