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Anticipated Laboratory Results for Different Causes of Hypercalcemia

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	Ionized Calcium	Total Calcium	PTH	PTHrP	Phosphorus	Calcidiol	Calcitriol
Granulomatous	↑	↑	↓N	↑N	↑N	N	↑N
Osteolytic	↑	↑	↓	↑N	↑N	N	N
PHPT	↑	↑	↑N	N	↓N	N	↑N
Vitamin D toxicosis	↑	↑	↓	N	↑	N	↑
Addison	↑	↑	↓N	N	↑N	N	↓N
Acute renal disease	↑	↑	↓N	N	↑N	N	↓N
Chronic renal disease	↓N	↑↓N	↑	N	↑N	↓N	↓N
Nutritional	↓N	↓N	↑	N	↑N	↓N	↓N
Tertiary HPT	↑	↑	↑	N	↑	↓N	↓N
Neoplasia	↑	↑	↓N	↑N	↓N	N	↑↓N
Idiopathic	↑	↑	↓N	N	↑N	↓N	↑↓N