Merck Manual

Please confirm that you are a health care professional

honeypot link

Praziquantel and Epsiprantel

By

Jozef Vercruysse

, DVM, Ghent University;


Edwin Claerebout

, DVM, PhD, DEVPC, Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University

Last full review/revision Sep 2014 | Content last modified Oct 2014

Praziquantel and epsiprantel are closely related analogues that have high efficacy against cestode parasites at relatively low dose rates but no effect on nematodes.

Praziquantel PO is highly effective against cestodes of ruminants (eg, Moniezia spp, Stilesia), horses (Anoplocephala perfoliata), dogs, cats, and poultry. The PO (5 mg/kg), SC (5.8 mg/kg), or spot-on (cats, 12 mg/kg) administration of praziquantel in dogs and cats is 100% effective against Dipylidium caninum, Taenia spp, and Echinococcus spp (both adult and immature forms). Praziquantel at a dosage of 40 mg/kg is also effective against Schistosoma infections in cattle (and people).

Epsiprantel at 5 mg/kg is used specifically to treat the common tapeworms of dogs and cats, including adult E granulosus.

Others also read
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Test your knowledge
Systemic Pharmacotherapeutics of the Cardiovascular System
Dogs and cats with left-side congestive heart failure (CHF) can develop respiratory distress due to pulmonary edema. Which of the following intravenous diuretics is the most appropriate treatment for life-threatening pulmonary edema caused by CHF?
Become a Pro at using our website 

Also of Interest

Become a Pro at using our website 
TOP