Drug	Dosage
Amiodarone	Dog: 8–10 mg/kg, PO, every 12–24 hr for 7–10 days, then reduce to 4–6 mg/kg/day for longterm treatment
Amlodipine	Dog: 0.1–0.2 mg/kg, PO, bid; or 0.2–0.4 mg/kg/day, PO
	Cat: 0.625–1.25 mg/cat, PO, once to twice daily
Aspirin (antiplatelet dosage)	Dog: 5–10 mg/kg, PO, every 1–2 days
	Cat: 1–2 mg/kg/day, PO; or ¼ of an 81-mg tablet/cat, PO, every 3 days (or twice per week)
Atenolol	Dog: 0.2–1 mg/kg, PO, bid
	Cat: 1–2.5 mg/kg, PO, bid; or 6.25–12.5 mg/cat, bid
Benazepril	Dog: 0.25–0.5 mg/kg, PO, once to twice daily
	Cat: 0.25–0.5 mg/kg, PO, bid; or 0.5 mg/kg/day, PO
Clopidogrel	Dog: loading dose for rapid onset of action (90 min) 10 mg/kg, PO (once); 1–2 mg/kg/day, PO, longterm
	Cat: ¼ of a 75-mg tablet (18.75 mg)/day/cat, PO
Diltiazem	Dog: 0.5–2 mg/kg, PO, tid (standard formulation); 1–4 mg/kg, PO, bid (sustained release)
	Cat: 7.5 mg/cat, PO, tid (standard formulation); 3–6 mg/cat, PO, once to twice daily (sustained release)
Dobutamine	Dog: 2.5–15 mcg/kg/min, CRI^a
Enalapril	Dog: 0.25–0.5 mg/kg, PO, bid
	Cat: 0.25–0.5 mg/kg, PO, bid; or 0.5 mg/kg/day, PO
Furosemide	Dog: 2–4 mg/kg, IV, IM, SC, every 1–6 hr; 0.25–1 mg/kg/hr, CRI; or 1–5 mg/kg, PO, bid-tid
	Cat: 0.5–2 mg/kg, IV, IM, SC, every 1–8 hr; 0.25–0.6 mg/kg/hr, CRI; or 1–2 mg/kg, PO, once to twice daily
Heparin	Dog: 100–200 U/kg, SC, tid-qid (unfractionated)
	Dog and cat: 100–200 IU/kg, SC, once to twice daily (low molecular weight)
Hydralazine	Dog: 0.5–3 mg/kg, PO, bid
Lidocaine	Dog: 2–4 mg/kg, IV; 25–75 mcg/kg/min, CRI
Mexiletine	Dog: 4–6 mg/kg, PO, tid
Nitroglycerin ointment 2% (1 in. = 15 mg)	Dog: 4–12 mg, topically, bid (maximum 15 mg/dog/dose)
	Cat: 2–4 mg/cat, topically, tid-qid for 1–2 days
Pimobendan	Dog, cat: 0.25–0.3 mg/kg, PO, bid
Procainamide	Dog: 4–6 mg/kg, PO, every 2–4 hr (regular formulation); 10–20 mg/kg, PO, tid (sustained release); 2–25 mg/kg, slow IV bolus to effect, or CRI at 25–40 mcg/kg/min
Quinidine sulfate	Dog: 5–10 mg/kg, IV, qid; or 6–20 mg/kg, PO, tid-qid
Quinidine gluconate	Dog: 6–20 mg/kg, IM, qid; or 6–20 mg/kg, PO, tid-qid
Sildenafil	Dog: 1–3 mg/kg, PO, bid-tid
Sotalol	Dog, cat: 1–2.5 mg/kg, PO, bid
Spironolactone	Dog: 1–2 mg/kg, PO, bid; or 2 mg/kg/day, PO
	Cat: 1–2 mg/kg, PO, once to twice daily
Torsemide	Dog: 0.25–0.4 mg/kg, PO, once to twice daily
^a CRI = constant-rate infusion

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Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Veterinary Manual was first published in 1955 as a service to the community. The legacy of this great resource continues as the Merck Veterinary Manual in the US and Canada and the MSD Manual outside of North America.