Clinicopathologic syndromes indistinguishable from acute bovine pulmonary emphysema and edema Pulmonary Emphysema, Edema, and Interstitial Pneumonia in Cattle Acute bovine pulmonary emphysema and edema (ABPEE) is one of the more common causes of acute respiratory distress in adult cattle on pasture. It usually occurs in the fall, 5–10 days after a... read more (ABPEE ) occur after ingestion of either moldy sweet potatoes infested with Fusarium solani or the wild mint Perilla frutescens.
Moldy sweet potato toxicity is due to the ingestion of a furanoterpenoid toxin produced by sweet potatoes (Ipomoea batatas) in response to infestation with the fungus F solani; the end result is production of the pneumotoxin 4-ipomeanol. Perilla ketone toxicity is due to ingestion of the leaves and seeds of the plant P frutescens (purple mint), which contains a pneumotoxin and is found in the southeastern US. The pathogeneses of both these conditions are similar to that of ABPEE, as is approach to treatment.