Nonregenerative anemias can be caused by nutritional deficiencies Nutritional Deficiency Anemia in Animals Nutritional deficiency anemias develop when micronutrients needed for RBC formation are not present in adequate amounts. Anemia develops gradually and may initially be regenerative but ultimately... read more , chronic disease Anemia of Chronic Disease in Animals Anemia of chronic disease can be characterized as mild to moderate, nonregenerative, normochromic, and normocytic. It is the most common form of anemia seen in animals. The anemia can be secondary... read more , renal disease Anemia Caused by Renal Disease in Animals Chronic renal disease is a common cause of nonregenerative anemia in animals. Erythropoietin is normally produced by the peritubular endothelial cells in the renal cortex. Animals with renal... read more , and primary bone marrow diseases Anemia Caused by Primary Bone Marrow Diseases in Animals Primary bone marrow disease or failure from any cause can lead to nonregenerative anemia and pancytopenia. With diffuse marrow involvement, granulocytes are affected first, followed by platelets... read more . Acute anemia will be nonregenerative until regeneration occurs in 3–4 days.