Foot-and-mouth disease RNA genome

a) The foot-and-mouth disease virus RNA genome contains a single open reading frame encoding a polyprotein that is processed to yield 15 mature products and a variety of precursors. b) The structural proteins, which make up the virus particle, are produced by processing the capsid precursor (P1-2A), and the products (60 copies of each) assemble with a single copy of the RNA genome into new virus particles.