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Immunodeficiency Diseases in Animals

By

Ian Tizard

, BVMS, PhD, DACVM, Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University

Last full review/revision Jun 2020 | Content last modified Jun 2020

Immunodeficiency diseases manifest clinically as a predisposition to infections. They are usually recognized when an animal makes multiple visits to a veterinarian for infections that would normally be relatively easy to control. Two major groups of immunodeficiency disease occur. One group is inherited as a result of mutations or other genetic disease. These primary or congenital immunodeficiency diseases usually develop in very young animals (<6 months of age). The second group of immunodeficiency diseases are secondary to some other stimulus such as a viral infection or tumor. These secondary or acquired diseases tend to occur in adult animals. One other general rule in diagnosing immunodeficiencies is that defects in the innate and antibody-mediated immune systems tend to result in uncontrollable bacterial infections, whereas defects in the cell-mediated immune system tend to result in overwhelming viral and fungal infections.

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Also see pet health information regarding immunologic diseases in dogs and immunologic diseases in cats.

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